In modern aesthetic medicine, increasing attention is paid not only to wrinkle masking but also to skin health restoration. Polynucleotides (PN) are highly purified salmon-derived DNA fragments with good biological compatibility with human tissues. They are used not to change facial features or add volume, but to activate the skin's natural regeneration processes.
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Rejuran
Name
1 procedure
Rejuran Face & Neck Regeneration (2 ml)
359€
Buy
For face and neck skin regeneration and overall skin quality improvement.
Rejuran S (1 ml)
259€
Buy
For improving scars, skin texture, and skin regeneration.
Rejuran Eye (1 ml)
279€
Buy
For under-eye skin regeneration and reduction of fine lines.
Procedure steps
1. Consultation and skin assessment
The specialist assesses the skin condition, discusses goals, and creates an individual procedure plan.
2. Area preparation
Skin is cleaned, disinfected, and treatment areas are marked.
3. Local anesthesia
If needed, a topical anesthetic cream is applied to make the procedure comfortable.
4. Polynucleotide injections
Rejuran polynucleotides are injected into the skin using fine needles or microneedles, applying the doctor’s chosen technique.
5. Skin soothing
Soothing care is applied after the procedure; a cold compress or calming cream may be used.
6. Home care and next steps
The doctor provides home care instructions-including sun protection, gentle skin care, and follow-up visits.
Rejuran - regenerating skin rejuvenation with polynucleotides
Regeneration based on biological compatibility
Rejuran uses highly purified salmon-derived polynucleotides that activate skin regeneration mechanisms without increasing facial volume. The procedure stimulates fibroblast activity and natural collagen and elastin renewal, leading to skin that is smoother, firmer, and better hydrated over time.
Practical effects and important patient considerations
Initial changes are typically visible after 2-4 weeks, with full effects developing over several months. Rejuran is especially suitable for those seeking a natural result without altering features; the doctor determines the number of procedures and intervals based on skin condition. The procedure uses very fine needles and is generally well tolerated.
Skin rejuvenation, collagen stimulation, skin quality improvement – What are Rejuran Polynucleotides?
Modern aesthetic medicine increasingly focuses not only on reducing the appearance of wrinkles but also on restoring overall skin health. One of the most advanced regenerative aesthetic medicine treatments is Rejuran Polynucleotides.
Polynucleotides (PN) are highly purified salmon DNA fragments with excellent biocompatibility with human tissues. They are used not to alter facial features or add volume, but to activate the skin’s natural regeneration processes.
Rejuran technology has been used for many years in South Korea and other countries around the world as an innovative solution for skin regeneration.
How does the Rejuran Polynucleotide treatment work?
Rejuran is based on the patented DOT™ (DNA Optimizing Technology), which enables the extraction of exceptionally high-purity polynucleotides.
Once introduced into the skin, polynucleotides:
activate fibroblast activity;
stimulate collagen and elastin production;
enhance tissue regeneration;
help restore damaged skin structure;
reduce the effects of oxidative stress and inflammatory processes;
strengthen the skin’s protective barrier;
improve the skin’s ability to retain moisture.
As a result, the skin becomes not only more beautiful but also healthier.
How is Rejuran different from hyaluronic acid fillers?
Although both treatments are performed through injections, their purpose is different.
Hyaluronic acid fillers restore lost volume or enhance facial contours.
Rejuran Polynucleotides do not add volume—they improve the quality of the skin itself and stimulate its natural regeneration.
For this reason, the treatment is particularly suitable for people who want to look younger while maintaining a natural appearance.
What skin concerns can Polynucleotides help address?
Rejuran is recommended for:
early signs of skin aging;
loss of skin firmness;
dull, tired-looking skin;
fine lines and wrinkles;
post-acne scars;
enlarged pores;
dehydrated skin;
skin damage caused by excessive sun exposure;
sensitive and thinning skin.
The treatment can be performed not only on the face but also around the eyes, on the neck, décolletage, and hands.
What skin regeneration results can you expect?
Since polynucleotides stimulate the skin’s natural regeneration processes, results develop gradually.
The most commonly observed improvements include:
brighter, more radiant skin;
smoother skin texture;
improved skin firmness;
greater skin elasticity;
reduced fine lines;
less visible pores;
softer post-acne scars;
healthier, better-hydrated skin.
As collagen production continues over time, skin quality may continue improving for several months after completing the treatment course.
A course of 3–4 treatments is generally recommended, with intervals of 3–4 weeks between sessions. Your physician or qualified aesthetic medicine specialist will always create an individualized treatment plan.
Who is the Rejuran treatment suitable for?
Rejuran is suitable for both women and men who want to:
improve skin quality;
slow down the skin aging process;
stimulate natural collagen production;
reduce fine lines and wrinkles;
improve skin elasticity;
reduce post-acne scars;
restore the skin’s natural glow.
The treatment is also frequently chosen as a preventive measure against premature skin aging.
Why choose Rejuran for skin rejuvenation and skin quality improvement?
Rejuran is more than just another “beauty injection.” It is a regenerative aesthetic medicine treatment focused on long-term improvement of skin quality.
Key benefits:
✔ supports natural skin regeneration;
✔ stimulates collagen and elastin production;
✔ improves skin texture and structure;
✔ does not alter facial features;
✔ excellent biological compatibility;
✔ scientifically studied mechanism of action.
Rejuran Polynucleotides at Era Esthetic Avenue
The specialists at “Era Esthetic Avenue” create an individualized treatment plan for every patient based on their skin condition, age, and desired results.
During the consultation, your specialist will determine whether Rejuran Polynucleotides are the most suitable option or whether combining the treatment with other skin quality improvement procedures would provide even better results.
If you are looking for a solution that does not simply mask the signs of skin aging but helps your skin regenerate naturally, Rejuran Polynucleotides are one of the most advanced regenerative aesthetic medicine treatments available today.
What you need to know
Come to the consultation without makeup. Inform about medications, allergies, and previous procedures. Avoid intense sun exposure and blood-thinning agents before the procedure if recommended.
The skin is cleaned and disinfected. If necessary, anesthetic cream is applied. Rejuran is injected with fine needles into marked areas. Procedure duration depends on the treatment area.
Mild redness, swelling, or minor subcutaneous bruises may occur, which resolve within a few days. Avoid sun, intense exercise, and hot treatments during the first 24-48 hours. Use the doctor’s recommended skincare.
The procedure uses highly purified salmon-derived polynucleotides with good biological compatibility. It must be performed by a qualified aesthetic medicine specialist who has assessed the patient’s individual condition.
The duration of results depends on skin condition, lifestyle, and individual characteristics. Maintenance procedures are usually recommended every 6-12 months.
Yes. The doctor may recommend combining Rejuran with other aesthetic medicine procedures to maximize skin quality improvement.
WE WERE THE FIRST IN LITHUANIA TO INTRODUCE THESE GOLD STANDARD* TECHNOLOGIES IN LASER DERMATOLOGY!
ULTHERA – non-surgical lifting of the skin, subcutaneous fat tissue and the superficial musculoaponeurotic system (SMAS).
ALEXANDRITE lasers – hair removal and pigmentation treatment. The most powerful PRO lasers in Lithuania; after a course, up to 95% of hair is removed.
VBEAM PERFECTA and PRIMA lasers – for treating redness and removing capillaries.
THERMAGE with the third-generation CPT system – thermolifting for skin tightening.
VELASHAPE III – anti-cellulite and circumference-reducing massage.
THE FIRST CLINICS IN LITHUANIA FOR THESE PROCEDURES:
FRAXEL DUAL fractional skin rejuvenation, CO2RE fractional skin rejuvenation, scar and stretch mark removal, OMNILUX red light therapy – acne treatment.
INTRACEUTICALS – oxygen skin therapy, HYDRAFACIAL with the TOWER system – professional facial cleansing.
*universally recognized as the most effective or leading technology for performing procedures and treatments.
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